A 501(c)(4) nonprofit organization dedicated to advancing legislation and policies aimed at increasing healthy human lifespan, with a focus on accelerating equitable access to next-generation therapies.
A4LI was founded at a pivotal moment, as groundbreaking advancements in longevity science highlight the immense potential for extending our healthspan. Yet, significant challenges remain like funding and regulation, which underscore the urgency of our mission. With a forward-thinking approach, we collaborate with academics, non-profits, longevity science investors, biotech innovators, and policymakers to overcome these barriers through strategic and impactful initiatives that reflect A4LI’s commitment to extending society’s healthspan.
Increased federal funding to advance aging research and accelerate the development of longevity medicines.
We advocate for clear FDA standards to streamline approval of safe, effective longevity medicines targeting aging biology.
Advocating for Congress to establish a national life expectancy goal to drive innovation and enhance public health.
Learn more about our past advocacy events that advanced the dialogue on promoting a healthy human lifespan.
Becoming a member of the Alliance for Longevity Initiatives (A4LI) connects you with a collective voice driving policies that support longevity science. Members gain exclusive access to events, expert discussions, and updates on cutting-edge longevity research, while enjoying discounts on longevity conferences products. A4LI members help amplify our mission and shape our future of longer, healthier lives for all.
Aging is the greatest risk factor for chronic diseases and conditions. Less than 1% of the National Institutes of Health (NIH) budget goes to aging biology research, despite being the main driver of the leading causes of death.
The aging U.S. population faces rising health challenges, with chronic diseases like heart disease, cancer, and Alzheimer’s leading the causes of death. Nearly 68% of adults over 65 live with multiple chronic conditions, emphasizing the growing impact of multi-morbidity. Declining life expectancy further underscores the need for improved healthcare strategies and preventive measures to address these issues and support healthy aging.
As the U.S. population ages, chronic diseases tied to the aging process—such as heart disease, cancer, and Alzheimer’s—continue to dominate public health concerns. Multi-morbidity, or living with multiple chronic conditions, affects a significant majority of older adults, straining our healthcare system. The emerging field of geroscience offers hope by focusing on the biological processes driving aging, aiming to delay disease onset and enhance overall healthspan. These innovations are crucial in addressing the health challenges of an aging nation.
While the NIH allocates about $3 billion annually to aging-related research, less than 1% goes towards the fundamental biology of aging. Meanwhile, private sector investments in longevity biotech are accelerating, surpassing $3 billion in 2023 to advance breakthroughs like regenerative medicine and gene therapy.
Join the Alliance for Longevity Initiatives (A4LI) in advocating for policies that promote healthy human lifespans. Engage by volunteering, signing petitions, or participating in events to support longevity research and equitable access to next-generation therapies.
The Alliance for Longevity Initiatives (A4LI) is a 501(c)(4) nonprofit organization whose mission is to advance legislation and policies that aim to increase healthy human lifespan, with a focus on accelerating equitable access to next-generation therapies.